In case you are interested in the latest trends in AI for Drug Discovery and you missed the conference in London, our senior scientific consultant Riccardo Martini wrote an extensive summary of it. Give it a read!
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For the fourth time, Discngine is ranked among the top 500 fastest-growing companies in France (Champions de la croissance 2022, Les Echos - leading economic paper in France). Discover the four pillars we focus on to become a European leader in life sciences research informatics!
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The short summary of the industry popular book “AI in Drug Design” written by our Senior Scientific Consultant Riccardo Martini. Give it a read!
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In 2020, Discngine faced a new challenge. It had grown to a size where doing the "classical" annual salary reviews was not possible anymore. We decided to set up a new system, more scalable and more reflective of our company culture.
It's been two years now since Discngine implemented the new recognition system, and it's time for us to look back on it.
On the 21st of October, Discngine hosted its first meetup - a 3-hour virtual event with customers and partners covering the “Digital Discovery” theme. Over 120 attendees had a great time hearing the latest scientific and business insights as well as networking.
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Introducing the Spotfire Web Application for KNIME (a.k.a. SWAK), a Discngine-built connector between two widely used tools in data analysis: KNIME and TIBCO Spotfire®.
Méliné is showing how simple it is to visualize a dataset’s chemical space by building a KNIME workflow projecting the dataset onto the chemical space, before visualizing it efficiently with TIBCO Spotfire® through the SWAK!
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As an official KNIME Partner, we at Discngine are extremely happy that the work accomplished with our client CENTOGENE resulted in a KNIME Success Story. Read more to discover the story behind the project!
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Cloud environment can bring a lot of benefits, to research-driven organizations, but shifting from an on-premises (local) to a Cloud environment can be challenging and sometimes scary. This article will outline an example of a French Biotech Startup that migrated its scientific software applications toolset to the Cloud and reveal the real-life advantages of this migration that exceeded expectations.
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Over the last two years, we observed a significant mindset change in life science research organizations towards the cloud technologies landscape. Less fear and skepticism, a better understanding of the capabilities, and rising expectations. Nevertheless, some obstacles specific to our business remain.
In this article, we explore five of the most common obstacles to Cloud shift for life science R&D and how to overcome them.
The purpose of this article is to illustrate how to apply some of 3decision’s features in scientific research. For this use case, the 3decision Subpocket Similarity Search is used to suggest modifications for the optimization of a small- molecule PROTAC. The Protein-Ligand interaction coloring by statistics is then used to evaluate docking poses of new compounds. The bromodomain-containing protein 4 – cereblon complex (BRD4-CBRN) and its degrader dBET23 are used as an example.
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Discngine’s 3decision team is partnering up with Nanome to bring a new dimension to structural analysis. With 3decision in VR, users will be able to entirely exploit the structural knowledge stored in 3decision in a new and advanced way to accelerate drug-design processes.
Read More![An innovative way of organizing data: How can 3decision® improve decision-making process? [Customer Success Story]](https://images.squarespace-cdn.com/content/v1/527ce929e4b0d974f5707b6b/1615136275319-V2R2V6RNY061AS08WIW1/thumbnail+2.png)
Manuel Cases Thomas, a Medicinal chemistry consultant and director at Senechaem was looking for a solution to help him use the full potential of data at hand and generate new design ideas. In this interview, he shares how 3decision® makes a difference in his daily work: from a scientific need to the impact on design ideas and successful project outcomes.
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I found my way to quickly learn new software: by validating its features. In this article, I am presenting the retrospective analysis of the detection of BCR-ABL1 allosteric binding site using the 3decision Pocket Explorer feature.
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The updated 3decision® version has some important new features for cross-team collaboration and structure-based drug design project management. A lot of improvements are made on the structure visualization UI as well.
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For the third time, Discngine is ranked among the TOP500 fastest-growing companies in France!
We would like to thank all of our customers for their trust which made this accomplishment possible.
We are very happy about this result which for us confirms the relevance of our products and services but also validates our organizational model…
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This short post shows how to quickly analyze larger collections of structures and check for common and different parts among such large sets of structures.
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The continuous increase in the available 3D structural data brings along changes in the medicinal chemistry field. Dr. George Sheppard, Senior Principal Research Scientist at AbbVie, shared his thoughts on the benefits for medicinal chemists using 3D information, current challenges and limitations, and proposed potential ways for improvement, in the following interview.
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The construction of accurate data sets prior to the in-silico experiments is a crucial first step in many SBDD projects. In our latest webinar, we explained how 3decision® can help ease and speed up this process. For better understanding, we presented three common use cases in SBDD using our platform.
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Google-owned company DeepMind has achieved to predict 3D protein shapes with high accuracy and speed using the AI program AlphaFold. Although still in the early phase, this method can have a significant impact on drug discovery, accelerating the development of new drugs. In this article, we are discussing the importance of getting ready for the new source of structural data and how to gain the most of structural knowledge.
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Delays, functionality, and ergonomics problems, poor choice of technologies, security flaws... When it comes to IT projects, the list of potential problems can be long, very long. To avoid this, Discngine is using a Delivery Management approach to ensure the successful completion of the project.
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